A Rhode Island man became the first patient worldwide to receive Biogen’s hotly debated Alzheimer’s drug outside of a clinical trial on Wednesday, a hospital spokesperson confirmed to Fox News.
Marc Archambault, 70 of Wakefield, received the infusion shortly before noon at Butler Hospital in Providence, according to spokesperson Raina Smith of Care New England. The patient met the criteria for people diagnosed with mild cognitive impairment or early Alzheimer’s disease, Smith said.
WHO SHOULD TAKE NEW ALZHEIMER'S DRUG? EXPERT WEIGHS IN
Dr. Stephen Salloway, director of the memory and aging program at Butler Hospital, patient Marc Archambault, and friend Karen Poole. (Photo courtesy of Care New England Health System and Butler Hospital)
"It’s transforming how we treat Alzheimer’s," Dr. Stephen Salloway, director of the memory and aging program at Butler Hospital, said at a press conference. "For those of you who don’t know, it’s a devastating disease."
"Marc actually tried out for aducanumab [trials] twice but he flunked because he did too well on his memory tests," Salloway said. "We knew he had Alzheimer’s and he was building up amyloid plaques in the brain and had an increased genetic risk for Alzheimer’s."
The patient, Archambault, also spoke during the press conference, thanking his doctors.
"It’s just amazing to think that this will be helpful and the other drugs that will come in the future so that my children don’t have to worry about it as well, and my family," Archambault said.
"It’s a slow situation, I still work, I’m a realtor," he continued, reflecting on his course of disease. "A few years ago I realized I was gonna have to retire...luckily my real estate brain is still here."
2 FDA COMMITTEE MEMBERS RESIGN OVER BIOGEN ALZHEIMER'S DRUG APPROVAL
The Food and Drug Administration last week approved Biogen’s Alzheimer’s drug albeit to mixed reviews. It is the first drug approved for Alzheimer's in nearly 20 years. Part of the controversy in the medical community surrounding the drug’s approval stems from data collected during two Phase 3 clinical trials. One study met the primary endpoint and showed a reduction in clinical decline, while the other did not. In November 2020, the Peripheral and Central Nervous System Drugs Advisory Committee had said it was not reasonable to consider clinical benefit of the drug based on one successful study.
Dr. Douglas Scharre, a neurologist and director of the division of Cognitive Neurology at Ohio State Wexner Medical Center and clinical investigator on Biogen’s studies, previously told Fox News that the antibody treatment works by clearing toxic amyloid proteins from brain tissue, though patients with late-stage Alzheimer’s disease are unlikely to benefit.
FDA OK'S BIOGEN'S ALZHEIMER'S DRUG: WHAT IS ACCELERATED APPROVAL?
"If the person is too far along in their disease, it’s not going to work, we don’t want to waste important health care dollars," Scharre told Fox News at the time.
"It's not a cure, it doesn't reverse anything, it's a pretty modest impact," Scharre said. "We’ll take it, we don't have it right now so we’ll take anything."
If a patient starts treatment early, studies suggested a 23% slow in decline.
Fox News' Alexandria Hein contributed to this report.
Business - Latest - Google News
June 17, 2021 at 03:45AM
https://ift.tt/2SwBITN
Biogen's debated Alzheimer's drug given to first patient - Fox News
Business - Latest - Google News
https://ift.tt/2Rx7A4Y
Bagikan Berita Ini
0 Response to "Biogen's debated Alzheimer's drug given to first patient - Fox News"
Post a Comment